Which brain region signals fullness and helps terminate eating behavior?

• A. Hypothalamus
• B. Lateral Hypothalamus
• C. Cerebellum
• D. Ventromedial Hypothalamus

Answer: (D)

The ventromedial hypothalamus acts as the fullness signal, serving as the satiety center that helps stop eating. It receives hormonal and nutrient signals (like leptin and insulin) that reflect the body's energy status, and when activated it reduces further food intake. Damage to this area can lead to overeating, while stimulating it tends to curb hunger, which is why it’s the best choice for signaling fullness and terminating a meal. In contrast, the lateral hypothalamus is more tied to hunger and initiating eating, and the cerebellum is involved in movement rather than feeding regulation.